The algorithm (called dynamic non-local means) is very effective on 4D medical images (i.e. contrast-dynamic sequences such as DCE-MRI, fMRI and dynamic PET). This implementation is straight-forward and is thus not efficient (computationally). However, it is quite easy to convert to c/c++ through mex.

dnlm\dnlm.m
....\estimate_noise_dwt.m
dnlm

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