Alzheimer' s disease currently in clinical diagnostic criteria is to determine whether the mutation occurred on hippocampal volume, extent of the disease and the shrinkage of hippocampal volume is closely related to the amount. Watershed algorithm is the biggest flaw is more serious problem of over-segmentation using watershed line of the theoretical minimum energy value, can be adjusted to obtain the outline of the watershed algorithm to limit over-segmentation.

hippocampal segmentation.doc

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